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Best Ergonomic Mouse 2025: Vertical, Trackball, Split & Classic (Global Picks)

Vertical Mouse

Vertical mice adopt a handshake-style design that raises the mouse body to about 45°–90°, keeping the wrist in a natural neutral posture . Compared with traditional mice, this design reduces forearm and wrist rotational torque, lowering muscle tension and pain during long sessions. Vertical mice are suitable for users with carpal tunnel syndrome or long-term office needs, effectively relieving wrist and forearm pressure and improving posture. Representative products include:

Logitech MX Vertical (Logitech)

  • Main features: 57° handshake angle design that reduces wrist pressure and muscle fatigue ; equipped with a 4000 DPI high-precision optical sensor which, compared to traditional 1000 DPI mice, reduces hand movement distance by 4× ; anti-slip surface and ergonomic curvature for comfortable grip .

  • Other highlights: Built-in 240mAh rechargeable battery; a full charge lasts about 4 months (1-minute quick charge gives 3 hours) ; supports multi-device quick switching (Logitech Unifying USB receiver and Bluetooth); 6 programmable buttons and precise middle-button file switching, etc.

  • Price range: About US$109 (≈ NT$3,600).

  • Handedness: Right-hand only.

  • Wired/Wireless: Wireless (Bluetooth and USB receiver; can be charged via cable or used wired).

  • Purchase link: Logitech – MX Vertical.

 

Evoluent VerticalMouse 4 (Evoluent)

  • Main features: Classic upright silhouette that keeps the arm in a natural neutral angle, avoiding excessive wrist twisting ; adjustable laser sensor, thumb rest, and extended bottom edge to further reduce wrist and forearm load .

  • Other highlights: Right-hand only; available in USB wireless (with receiver; AA batteries) and wired versions; two thumb-side auxiliary buttons with driver for more programmable shortcuts.

  • Price range: About US$116 (≈ NT$3,800).

  • Handedness: Right-hand only.

  • Wired/Wireless: Wireless (USB receiver, battery) and wired versions.

  • Purchase link: Amazon – Evoluent VerticalMouse 4 (official purchase channels also available).

 

Logitech Lift (Logitech)

  • Main features: 57° handshake angle design for a natural, comfortable wrist posture ; 400–4000 DPI optical sensor (customizable sensitivity), 6 buttons (left/right, forward/back, wheel, and middle) ; refined anti-slip grip with ergonomic fit.

  • Other highlights: Suitable for small/medium hands; available in left- and right-hand models; uses 1×AA battery with up to 24 months’ life ; wireless (Bluetooth or Logi Bolt USB receiver); Logi Options+ software enables button and gesture customization.

  • Price range: About US$70–80 (≈ NT$2,200–2,500).

  • Handedness: Left- and right-hand models.

  • Wired/Wireless: Wireless (Bluetooth and receiver).

  • Purchase link: Logitech – Lift (also available on Amazon, etc.).

 

Anker Wireless Vertical Mouse (Anker)

  • Main features: Handshake-style vertical angle that encourages a natural neutral wrist/forearm posture ; supports 800/1200/1600 DPI optical tracking, offering higher precision than typical mice ; 5 buttons including forward/back, ideal for long browsing and office use.

  • Other highlights: Right-hand design; 2.4GHz USB receiver (stows in the base), uses 2×AAA batteries (up to ~18 months); plug-and-play.

  • Price range: About US$20–30 (≈ NT$600).

  • Handedness: Right-hand only.

  • Wired/Wireless: Wireless (USB receiver; batteries).

  • Purchase link: Amazon – Anker 2.4G Wireless Vertical Ergonomic Mouse.

 

Trackball Mouse

A trackball mouse keeps the body stationary while the user pushes a ball with the thumb or other fingers to move the cursor, requiring almost no wrist movement . This design allows shoulders and forearms to remain neutral and reduces the risk of repetitive strain injuries, especially for users prone to shoulder or wrist fatigue . With its small footprint and stability, it suits tight workspaces. Trackballs come in thumb-operated and finger-operated types; representative products include:

Logitech MX ERGO (Logitech)

  • Main features: Thumb-ball with adjustable tilt angle (0° or 20°) for a more natural forearm posture, reducing about 20% hand muscle fatigue ; users can control the cursor without moving the whole hand—ideal for space-limited setups .

  • Other highlights: Full-palm support curvature and anti-slip grip; precision optical tracking with a dedicated button to toggle precision/fast modes ; built-in 500mAh battery (about 4 months per charge; 1-minute quick charge for 1 day) ; Bluetooth and USB receiver wireless, plus Flow for multi-computer switching.

  • Price range: About US$100 (≈ NT$3,200).

  • Handedness: Right-hand only (optimized for right-hand design).

  • Wired/Wireless: Wireless (Bluetooth and Logitech Unifying receiver; rechargeable).

  • Purchase link: Logitech – MX ERGO.

 

Logitech ERGO M575 (Logitech)

  • Main features: Thumb-controlled ball lets users move the cursor by finger motion alone, with minimal palm/arm movement, greatly reducing wrist and forearm range of use ; ergonomic contour fits the right hand for long-term comfort.

  • Other highlights: Precision wheel (supports left-right scrolling); Bluetooth 5.1 low-energy and Logi Bolt USB receiver dual connectivity; 1×AA battery for about 18 months ; plug-and-play; button customization via Logi Options+ software.

  • Price range: About US$55 (≈ NT$1,800).

  • Handedness: Right-hand only.

  • Wired/Wireless: Wireless (Bluetooth and USB receiver; battery powered).

  • Purchase link: Logitech – ERGO M575.

 

Kensington Expert Wireless (Kensington)

  • Main features: Large 55mm trackball with outer scroll ring enabling horizontal scrolling ; detachable palm rest supports the hand to reduce wrist pressure; ambidextrous body for both left and right hands .

  • Other highlights: Four programmable buttons; Bluetooth LE and 2.4GHz USB wireless (stowable receiver); Diamond Eye optical tracking (1000 DPI); power-saving mode and power control; compatible with Windows/Mac/Chrome.

  • Price range: About US$100 (≈ NT$3,200).

  • Handedness: Ambidextrous.

  • Wired/Wireless: Wireless (Bluetooth and 2.4GHz USB receiver; two AAA batteries; months of runtime).

  • Purchase link: Amazon – Kensington Expert Wireless Trackball.

 

Kensington Orbit Wireless Trackball (Kensington)

  • Main features: Mid-size 40mm ball with outer scroll ring for vertical/horizontal scrolling; symmetrical design for left/right-hand use, reducing wrist/hand movement and helping relieve repetitive stress ; accurate optical tracking with adjustable 400/800/1200/1600 DPI.

  • Other highlights: Dual wireless (2.4GHz USB and Bluetooth LE) with 128-bit AES encryption; detachable soft palm rest; 3 programmable buttons and wheel middle-click; Mac/Windows compatible.

  • Price range: About US$80 (≈ NT$2,500).

  • Handedness: Ambidextrous.

  • Wired/Wireless: Wireless (Bluetooth and 2.4GHz USB receiver).

  • Purchase link: Amazon – Kensington Orbit Wireless Trackball.

 

Split/Adjustable Ergonomic Mouse

These mice typically offer adjustable structures, allowing users to tune grip angles or support positions according to hand size and habits . For example, mice with adjustable body tilt and thumb support provide a more personalized comfort level, suiting users with high posture demands or who need customized support. Representative products include:

Contour UniMouse (Contour)

  • Main features: Adjustable vertical mouse with a patented angle hinge enabling a 35°–70° grip angle ; five-way adjustable thumb support (forward/backward, inward/outward, up/down) to fit individual hand shapes ; ergonomic right-hand contour to significantly reduce wrist and thumb-joint pressure.

  • Other highlights: 6 programmable buttons; supports left/right-hand variants (this is the right-hand version; a left-hand version is available); available in wireless or wired; USB charging (long-life battery) or use-while-charging; can pair with Logi Options+ to adjust DPI and button functions.

  • Price range: About US$89 (≈ NT$2,900).

  • Handedness: Right-hand (left-hand also available).

  • Wired/Wireless: Wired USB (rechargeable wireless also available).

  • Purchase link: Contour – UniMouse.

 

Goldtouch Semi-Vertical Mouse (Goldtouch)

  • Main features: 66° semi-vertical tilt (between traditional and vertical mice) with an ergonomic angle to relax the wrist ; unique detachable “palm support” accessory lifts the palm to reduce tabletop friction ; anti-slip grip and rubberized coating for comfortable hold.

  • Other highlights: Built-in forward/back buttons for easier browsing; includes four removable weight modules (5g×4) to customize balance; USB 2.4GHz wireless dongle ; driverless plug-and-play; two AAA batteries included (months of life).

  • Price range: About US$99 (≈ NT$3,200).

  • Handedness: Right-hand only (medium/large size options).

  • Wired/Wireless: Wireless (2.4GHz USB receiver).

  • Purchase link: Goldtouch – Semi-Vertical Mouse.

 

Classic Ergonomic-Shaped Mouse

This category features classic ergonomic contours, usually with a right-hand palm-fitting curve where concave and convex zones align with the palm and thumb . The “thumb rest + palm support” design distributes hand pressure and reduces wrist load. Suitable for office and general users, it remains comfortable during long use. Representative products include:

Logitech MX Master 3S (Logitech)

  • Main features: High-precision Darkfield optical sensor with 200–8000 DPI range ; 7 function buttons (left/right, forward/back, app switch, smart wheel mode switch, middle, gesture button), plus thumb side wheel and gesture button for multi-task shortcuts ; MagSpeed electromagnetic wheel for silky, ultra-fast scrolling and pixel-level precision.

  • Other highlights: Ergonomic right-hand curve with thumb groove and palm-supporting thumb rest; built-in 500mAh battery with 1-minute quick charge for 3+ hours ; wireless via Bluetooth or Logi Bolt receiver; connects to 3 devices and uses Flow for cross-device drag-and-drop; fully programmable via Logi Options+.

  • Price range: About US$90–110 (≈ NT$2,800–3,500).

  • Handedness: Right-hand only.

  • Wired/Wireless: Wireless (Bluetooth and USB receiver; rechargeable).

  • Purchase link: Logitech – MX Master 3S.

 

Microsoft Sculpt Ergonomic Mouse (Microsoft)

  • Main features: Ergonomically high-arched design to keep wrist and forearm at a natural holding angle, reducing pressure on the carpal tunnel area ; recessed thumb scoop maintains natural spacing between thumb and palm. The mouse includes a 4-way scroll wheel for vertical and horizontal scrolling ; a dedicated Windows button opens the Start menu with one press .

  • Other highlights: Back button for quick navigation; 2.4GHz USB receiver connection (requires a USB-A port) ; right-hand only design; plastic + silicone materials give a soft palm rest feel; no Logitech Options-like customization software.

  • Price range: About US$80 (≈ NT$2,500).

  • Handedness: Right-hand only.

  • Wired/Wireless: Wireless (2.4GHz USB receiver included).

  • Purchase link: Incase – Sculpt Ergonomic Mouse.